Genetic diagnosis before implantation
نویسندگان
چکیده
منابع مشابه
Pre-implantation genetic diagnosis.
Pre-implantation genetic diagnosis (PGD) was first pioneered at Hammersmith Hospital, London, United Kingdom, in 1989 and allows the genetic sampling and testing of the early human embryo prior to being transferred to the uterus to start a pregnancy. Although occasionally controversial, PGD is now well established in several countries and in vitro fertilisation (IVF) centres around the world. I...
متن کاملPre-implantation genetic diagnosis.
Genetic disorders are a major cause of miscarriage and fetal death. Pre-implantation genetic diagnosis (PGD) can be used to diagnose genetic defects before pregnancy has occurred by creating embryos by IVF, then removing single cells which are genetically analysed using FISH or PCR. Although successful, the techniques have many difficulties because they are highly specialised and at the extreme...
متن کاملPre-implantation genetic diagnosis in Hong Kong.
This paper presents the first two successful cases of pre-implantation genetic diagnosis in Hong Kong and discusses the indications and the advantages over prenatal diagnosis. Patients should be informed about the procedure and extensively counselled about the possibility of misdiagnosis and the need for conventional prenatal diagnosis during pregnancy.
متن کاملPre-implantation genetic diagnosis and pre-implantation genetic screening: two years experience at a single center
Objective Indications for preimplantation genetic diagnosis (PGD)/preimplantation genetic screening (PGS) cycles and clinical outcomes were evaluated at CHA Gangnam Medical Center. Methods This is retrospective cohort study. All patients (n=336) who went through in vitro fertilization (IVF)-PGD/PGS cycles (n=486) between January 2014 and December 2015 were included in Fertility Center of CHA ...
متن کاملPre-Implantation Genetic Screening Techniques: Implications for Clinical Prenatal Diagnosis.
Chromosomal aneuploidy is responsible for a significant proportion of pregnancy failures, whether conceived naturally or through in vitro fertilization (IVF). In an effort to improve the success rate of IVF, screening embryos for aneuploidy - or pre-implantation genetic screening (PGS) - has been proposed as a means of ensuring only euploid embryos are selected for transfer. Early PGS approache...
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ژورنال
عنوان ژورنال: BMJ
سال: 1997
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.315.7112.828